Mon-Sat 09:00AM-07:00PM
Book Appointment
Book Appointment

Limbal Stem Cell Deficiency

Our Treatments

  1. Cataract Treatment
  2. Glaucoma
  3. Oculoplasty Treatment
  4. FEMTO-Z8
  5. Amblyopia
  6. Contact Lenses
  7. Cornea
  8. Diabetic Retinopathy
  9. Dry Eye
  10. ICL
  11. Keratoplasty
  12. Laser Eye Surgeries
  13. Lasik
  14. Trans PRK Surgery
  15. SMILE
  16. Limbal Stem Cell Deficiency
  17. Low Vision Aids
  18. Myopia Management
  19. Neuro Ophthalmology
  20. Paediatric Ophthalmology
  21. Retina and Uvea
  22. Squint

LIMBAL STEM CELL DEFICIENCY (LSCD)

Our team of expert ophthalmologists at Swarup Eye Centre is dedicated to providing cutting-edge treatment for Limbal Stem Cell Deficiency through Simple Limbal Epithelial Transplant (SLET), restoring vision and improving quality of life for patients with corneal surface disorders.

SLET is an innovative surgical technique designed to restore the corneal surface in patients with limbal stem cell deficiency (LSCD). This technique involves transplanting limbal epithelial cells from a healthy eye to the affected eye to promote cell growth and healing.


Limbal Stem Cell Deficiency

Understanding Limbal Stem Cell Deficiency (LSCD):

LSCD occurs when the limbal stem cells, responsible for regenerating the corneal epithelium, are damaged which could lead to severe ocular surface issues. This also results in the conjunctival tissue growing over the cornea. If left untreated, LSCD can result in significant vision impairment or blindness.

Why Choose SLET at Swarup Eye Centre?

  • Expert surgeon Dr. Rishi Swarup is a highly skilled and experienced ophthalmologist who specializes in SLET surgery
  • Impressive success rates with significant improvements in vision and overall eye health
  • State-of-the-art facilities and technology
  • Comprehensive pre and post-operative care

Common Causes of LSCD:

  • Chemical burns: Exposure to chemicals that damage the limbal stem cells
  • Trauma: Physical injury to the eye affecting the limbal region
  • Contact lens-related complications: Long-term use of contact lenses can sometimes lead to limbal stem cell damage
  • Inflammatory diseases: Conditions such as Stevens-Johnson syndrome or ocular cicatricial pemphigoid
  • Congenital conditions: Some people may be born with conditions like aniridia, where the limbal stem cells are underdeveloped or absent

What is SLET?

SLET (Simple Limbal Epithelial Transplant) is an innovative surgical technique designed to restore the corneal surface. The procedure involves several key steps:

  • Preparation: The donor eye is prepped, and a limbal biopsy is performed.
  • Transplantation: The harvested limbal tissue is cut into smaller pieces and placed on the amniotic membrane, which is secured over the corneal surface of the affected eye.
  • Post-operative Care: A bandage contact lens is applied to protect the transplant and facilitate healing.

Advantages of SLET:

  • Single-Stage Procedure: Unlike other techniques that may require multiple surgeries or extensive laboratory work, SLET can be performed in a single operation.
  • Cost-Effective: This method is particularly beneficial in resource-limited settings as it is a single stage without the need for costly equipment.
  • Minimally Invasive: The technique uses a small amount of limbal tissue (approximately 3-4 mm), making it less invasive for the donor eye and reducing recovery time.
  • Minimal Donor Site Impact: The technique conservatively uses a small amount of tissue from the donor eye, reducing potential complications.
  • Rapid Recovery: Corneal epithelialization typically occurs within 2 weeks, faster in children.

Outcomes and Considerations:

  • Factors Affecting the Outcome: Acid injuries, severe symblepharon, or combined keratoplasty may reduce success rates.
  • Complications: Graft displacement (10-18%) or recurrent conjunctivalization can occur but are manageable.
  • Visual Gains: Over 67% of patients achieve 20/60 vision or better, with faster recovery in children.

Expert Consultation at Swarup Eye Centre:

Swarup Eye Centre, a renowned Hospital in Hyderabad for over 64 years, offers top-notch care with experienced ophthalmologists and state-of-the-art facilities. The center has adopted this technique to treat partial and total LSCD, achieving outcomes comparable to global standards. SLET represents an advantageous shift in corneal regeneration, offering a lifeline to patients who previously had limited options. By prioritizing innovation and accessibility, Swarup Eye Centre continues to be at the forefront of advanced ophthalmic treatments.

Frequently Asked Questions

  • How long does the SLET procedure take?
    The procedure typically takes approximately 1-2 hours, depending on the complexity of the case.
  • What is the recovery time after SLET?
    Initial healing occurs within 2 weeks, but complete recovery and visual improvement may take several months.
  • Is SLET suitable for all types of LSCD?
    SLET is effective for many cases of LSCD, but the suitability depends on the specific cause and severity of the condition. Dr. Rishi Swarup will evaluate each case individually.
  • What are the success rates of SLET?
    Success rates are generally high, with over 67% of patients achieving significantly improved vision, though results can vary based on individual factors.